Phase one
Initiation Phase

Establish NDA for confidential discussions

Define project scope, goals, timeline, and data availability

RES submits project proposal
The initiation phase focuses on understanding the client’s request and defining the project scope, deliverables, budget, and timeline. We also conduct a preliminary analysis of the biology and available data to guide the modeling approach.

Phase two
Execution Phase

Develop detailed description of the biological system

Build model integrating biological knowledge and data

Calibrate and refine the model through testing and validation

Create case studies to demonstrate model insights
The execution phase builds confidence in the model through scientific analysis. We review literature and internal data, identify key assumptions, perform sanity checks, and calibrate the model to accurately represent the biological system.

Phase three
Final Phase

Deliver project and regulatory report
The final phase focuses on generating actionable insights from the model. Results may include first-in-human dose predictions, affinity requirements, PK attributes, optimal dosing strategies, and efficacy versus toxicity analysis. These findings are compiled into a comprehensive report suitable for internal decision-making or regulatory submission.

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